Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline
Long non-coding RNA (lncRNA) plays important roles in many diseases, including pulmonary hypertension. The anti-diabetic drug metformin has been discovered to have protective effect on experimental pulmonary artery hypertension (PAH). However, the exact mechanism of metformin on the expression of ln...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332219300435 |