Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline

Long non-coding RNA (lncRNA) plays important roles in many diseases, including pulmonary hypertension. The anti-diabetic drug metformin has been discovered to have protective effect on experimental pulmonary artery hypertension (PAH). However, the exact mechanism of metformin on the expression of ln...

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Bibliographic Details
Main Authors: Zengxian Sun, Yun Liu, Feng Yu, Yi Xu, Li Yanli, Naifeng Liu
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219300435