Mitochondria Retrograde Signaling and the UPRmt: Where Are We in Mammals?

Mitochondria Retrograde Signaling and the UPRmt: Where Are We in Mammals?

Mitochondrial unfolded protein response is a form of retrograde signaling that contributes to ensuring the maintenance of quality control of mitochondria, allowing functional integrity of the mitochondrial proteome. When misfolded proteins or unassembled complexes accumulate beyond the folding capa...

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Bibliographic Details
Main Authors: Thierry Arnould, Sébastien Michel, Patricia Renard
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondria
unfolded protein response
cell signaling
gene expression
Online Access:http://www.mdpi.com/1422-0067/16/8/18224

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