Mitochondria Retrograde Signaling and the UPRmt: Where Are We in Mammals?
Mitochondrial unfolded protein response is a form of retrograde signaling that contributes to ensuring the maintenance of quality control of mitochondria, allowing functional integrity of the mitochondrial proteome. When misfolded proteins or unassembled complexes accumulate beyond the folding capa...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/16/8/18224 |