The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway

Abstract Background The telomerase/telomere interacting protein PinX1 has been suggested as a tumor suppressor. However, the clinical and biological significance of PinX1 in human non-small cell lung cancer (NSCLC) is unclear. Methods PinX1 gene/expression pattern and its association with NSCLC pati...

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Bibliographic Details
Main Authors: Xiao-Peng Tian, Xiao-Han Jin, Mei Li, Wei-Juan Huang, Dan Xie, Jia-Xing Zhang
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Molecular Cancer
Subjects:
P15
Online Access:http://link.springer.com/article/10.1186/s12943-017-0637-4