Design, Synthesis and Cytotoxic Activities of Novel Aliphatic Amino-Substituted Flavonoids

A series of flavonoids 9a–f, 13b, 13d, 13e and 14a–f bearing diverse aliphatic amino moieties were designed, synthesized and evaluated for their cytotoxic activities against the ECA-109, A-549, HL-60, and PC-3 cancer cell lines. Most of the compounds exhibited moderate to good activities. The struct...

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Bibliographic Details
Main Authors: Guannan Liu, Zhen Ge, Mengdan Zhao, Yifeng Zhou
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/11/14070