Design, Synthesis and Cytotoxic Activities of Novel Aliphatic Amino-Substituted Flavonoids
A series of flavonoids 9a–f, 13b, 13d, 13e and 14a–f bearing diverse aliphatic amino moieties were designed, synthesized and evaluated for their cytotoxic activities against the ECA-109, A-549, HL-60, and PC-3 cancer cell lines. Most of the compounds exhibited moderate to good activities. The struct...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-11-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/18/11/14070 |