Platelet factor 4 promotes rapid replication and propagation of Dengue and Japanese encephalitis virusesResearch in context

Background: Activated platelets release cytokines/proteins including CXCL4 (PF4), CCL5 and fibrinopeptides, which regulate infection of several pathogenic viruses such as HIV, H1N1 and HCV in human. Since platelet activation is the hallmark of Dengue virus (DV) infection, we investigated the role of...

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Bibliographic Details
Main Authors: Amrita Ojha, Angika Bhasym, Sriparna Mukherjee, Gowtham K. Annarapu, Teena Bhakuni, Irshad Akbar, Tulika Seth, Naval K. Vikram, Sudhanshu Vrati, Anirban Basu, Sankar Bhattacharyya, Prasenjit Guchhait
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641830553X