Caveolae and scaffold detection from single molecule localization microscopy data using deep learning.

Caveolae are plasma membrane invaginations whose formation requires caveolin-1 (Cav1), the adaptor protein polymerase I, and the transcript release factor (PTRF or CAVIN1). Caveolae have an important role in cell functioning, signaling, and disease. In the absence of CAVIN1/PTRF, Cav1 forms non-cave...

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Bibliographic Details
Main Authors: Ismail M Khater, Stephane T Aroca-Ouellette, Fanrui Meng, Ivan Robert Nabi, Ghassan Hamarneh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211659