NLRP2 Regulates Proinflammatory and Antiapoptotic Responses in Proximal Tubular Epithelial Cells

NLRP2 Regulates Proinflammatory and Antiapoptotic Responses in Proximal Tubular Epithelial Cells

Nod-like Receptor Pyrin domain containing proteins (NLRPs) expressed by resident renal cells may contribute to the pathogenesis of multiple renal diseases. Cystinosis is a genetic disorder that affects kidney and particularly proximal tubular epithelial cells (PTEC). Here, we investigated the expres...

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Bibliographic Details
Main Authors: Marianna N. Rossi, Antonia Pascarella, Valerio Licursi, Ivan Caiello, Anna Taranta, Laura R. Rega, Elena Levtchenko, Francesco Emma, Fabrizio De Benedetti, Giusi Prencipe
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NLRP2
proximal tubular epithelial cells
inflammation
cytokines
apoptosis
cystinosis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00252/full

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https://www.frontiersin.org/article/10.3389/fcell.2019.00252/full

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