The Time is Crucial for Ex Vivo Expansion of T Regulatory Cells for Therapy
Ex vivo expanded CD4 + CD25 high CD127 - T regulatory cells (Tregs) are recognized as a promising candidate for immunosuppressive therapy in humans. However, due to the plasticity of Tregs lineage and artificial environment present during ex vivo expansion, Tregs easily lose suppressive activity. He...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2011-12-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368911X566217 |