Therapeutic Strategies against Epstein-Barr Virus-Associated Cancers Using Proteasome Inhibitors

Therapeutic Strategies against Epstein-Barr Virus-Associated Cancers Using Proteasome Inhibitors

Epstein-Barr virus (EBV) is closely associated with several lymphomas (endemic Burkitt lymphoma, Hodgkin lymphoma and nasal NK/T-cell lymphoma) and epithelial cancers (nasopharyngeal carcinoma and gastric carcinoma). To maintain its persistence in the host cells, the virus manipulates the ubiquitin-...

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Bibliographic Details
Main Authors: Kwai Fung Hui, Kam Pui Tam, Alan Kwok Shing Chiang
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Viruses
Subjects:
Epstein-Barr virus
proteasome inhibitor
apoptosis
cell cycle
lytic reactivation
Epstein-Barr virus nuclear antigen (EBNA)-3C
Online Access:https://www.mdpi.com/1999-4915/9/11/352

Internet

https://www.mdpi.com/1999-4915/9/11/352

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