Ubiquitin and ubiquitin-like modifiers modulate NK cell-mediated recognition and killing of damaged cells

Ubiquitin and ubiquitin-like modifiers modulate NK cell-mediated recognition and killing of damaged cells

Efficient elimination of transformed and virus-infected cells by natural killer (NK) cells mainly depends on the recognition of “induced self” ligands by activating receptors, including NKG2D and DNAM1. The surface expression of these ligands in stressed or diseased cells results from the integratio...

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Bibliographic Details
Main Authors: Rosa Molfetta, Beatrice Zitti, Angela Santoni, Rossella Paolini
Format: Article
Language:English
Published: American Institute of Mathematical Sciences 2017-11-01
Series:AIMS Allergy and Immunology
Subjects:
NK cells
activating receptors
activating ligands
ubiquitination
SUMOylation
Online Access:http://www.aimspress.com/Allergy/article/1711/fulltext.html

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http://www.aimspress.com/Allergy/article/1711/fulltext.html

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