Hypoxic tumour cell-derived exosomal miR-340-5p promotes radioresistance of oesophageal squamous cell carcinoma via KLF10

Hypoxic tumour cell-derived exosomal miR-340-5p promotes radioresistance of oesophageal squamous cell carcinoma via KLF10

Abstract Background Radiotherapy resistance is a major obstacle in the treatment of oesophageal squamous cell carcinoma (OSCC). Hypoxia is a critical cause of radioresistance. However, the communication between hypoxic cells and aerobic cells via exosomes during the transfer of radiation resistance...

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Bibliographic Details
Main Authors: Fangyu Chen, Bing Xu, Jie Li, Xi Yang, Junjie Gu, Xijuan Yao, Xinchen Sun
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hypoxia
Extracellular vesicles
miRNA
Oesophageal cancer
Radiotherapy
Online Access:https://doi.org/10.1186/s13046-021-01834-9

Internet

https://doi.org/10.1186/s13046-021-01834-9

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