Downregulation of miR-637 promotes vascular smooth muscle cell proliferation and migration via regulation of insulin-like growth factor-2

Downregulation of miR-637 promotes vascular smooth muscle cell proliferation and migration via regulation of insulin-like growth factor-2

Abstract Background Dysregulation of the proliferation and migration of vascular smooth muscle cells (VSMCs) is a crucial cause of atherosclerosis. MiR-637 exerts an antiproliferative effect on multiple human cells. Its impact on atherosclerosis remains largely unexplored. Methods Real-time PCR was...

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Bibliographic Details
Main Authors: Ning Yang, Bo Dong, Yanqiu Song, Yang Li, Lu Kou, Jingyu Yang, Qin Qin
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
miR-637
IGF-2
VSMC
Atherosclerosis
Online Access:http://link.springer.com/article/10.1186/s11658-020-00222-z

Internet

http://link.springer.com/article/10.1186/s11658-020-00222-z

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