Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma

Anaplastic lymphoma kinase-(ALK-) positive large B-cell lymphoma (ALK+ LBCL) is a rare, aggressive tumor characterized by an immunoblastic or plasmablastic morphologic appearance, expression of ALK, CD138, CD45, EMA, and often IgA by immunohistochemistry, and characteristic chromosomal translocation...

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Bibliographic Details
Main Authors: Elizabeth A. Morgan, Alessandra F. Nascimento
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2012/529572