Evolution of bow-tie architectures in biology.

Bow-tie or hourglass structure is a common architectural feature found in many biological systems. A bow-tie in a multi-layered structure occurs when intermediate layers have much fewer components than the input and output layers. Examples include metabolism where a handful of building blocks mediat...

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Bibliographic Details
Main Authors: Tamar Friedlander, Avraham E Mayo, Tsvi Tlusty, Uri Alon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004055