Bradykinin preconditioning improves therapeutic potential of human endothelial progenitor cells in infarcted myocardium.

OBJECTIVES: Stem cell preconditioning (PC) is a powerful approach in reducing cell death after transplantation. We hypothesized that PC human endothelial progenitor cells (hEPCs) with bradykinin (BK) enhance cell survival, inhibit apoptosis and repair the infarcted myocardium. METHODS: The hEPCs wer...

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Bibliographic Details
Main Authors: Zulong Sheng, Yuyu Yao, Yefei Li, Fengdi Yan, Jie Huang, Genshan Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3846887?pdf=render