Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model

Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model

Fibroblast activation protein (FAP) is a specific serine proteaseexpressed in tumor stroma proven to be a stimulatory factor inthe progression of some cancers. The purpose of this studywas to investigate the effects of FAP knockdown on tumorgrowth and the tumor microenvironment. Mice bearing 4T1subc...

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Bibliographic Details
Main Authors: Fan Cai, Zhiyong Li, Chunting Wang, Shuang Xian, Guangchao Xu, Feng Peng, Yuquan Wei, You Lu
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-05-01
Series:BMB Reports
Subjects:
Angiogenesis
Breast cancer
Fibroblast activation protein
RNA interference
Tumor microenvironment
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI3MTFAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni01JTVEMTMwNTI5MjIyNl8lMjgyNTItMjU3JTI5Qk1CXzEyLTE3Mi5wZGY=

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http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI3MTFAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni01JTVEMTMwNTI5MjIyNl8lMjgyNTItMjU3JTI5Qk1CXzEyLTE3Mi5wZGY=

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