The synthesis of the 2,3-difluorobutan-1,4-diol diastereomers

The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2,3-difluorobutane-1,4-diol, as well as the synthesis of the corresponding syn-diastereomer. Both targets were synt...

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Bibliographic Details
Main Authors: Robert Szpera, Nadia Kovalenko, Kalaiselvi Natarajan, Nina Paillard, Bruno Linclau
Format: Article
Language:English
Published: Beilstein-Institut 2017-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.13.280