Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts

<p>Abstract</p> <p>Background</p> <p>Small airway narrowing is an important pathology which impacts lung function in chronic obstructive pulmonary disease (COPD). The accumulation of fibroblasts and myofibroblasts contribute to inflammation, remodeling and fibrosis by p...

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Bibliographic Details
Main Authors: Tannheimer Stacey L, Wright Clifford D, Salmon Michael
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Respiratory Research
Subjects:
Online Access:http://respiratory-research.com/content/13/1/28