Galloyl-Hexahydroxydiphenoyl (HHDP)-Glucose Isolated From Punica granatum L. Leaves Protects Against Lipopolysaccharide (LPS)-Induced Acute Lung Injury in BALB/c Mice

Galloyl-Hexahydroxydiphenoyl (HHDP)-Glucose Isolated From Punica granatum L. Leaves Protects Against Lipopolysaccharide (LPS)-Induced Acute Lung Injury in BALB/c Mice

The hydroalcoholic extract and ethyl acetate fraction of Punica granatum leaves have been known to exhibit anti-inflammatory activities. In this study, we investigated the therapeutic effects of galloyl-hexahydroxydiphenoyl (HHDP)-glucose isolated from pomegranate leaves on lipopolysaccharide (LPS)-...

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Bibliographic Details
Main Authors: Aruanã Joaquim Matheus Costa Rodrigues Pinheiro, Aleff Ricardo Santos Mendes, Milena Dara Farias de Jesus Neves, Carla Máximo Prado, Márcia Isabel Bittencourt-Mernak, Fernanda Paula Roncon Santana, João Henrique G. Lago, Joicy Cortez de Sá, Claudia Quintino da Rocha, Eduardo Martins de Sousa, Valéria Costa Fontes, Marco Augusto Gregolin Grisoto, Angela Falcai, Lidio Gonçalves Lima-Neto
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
pomegranate
galloyl-HHDP-glucose
acute lung injury
anti-inflammatory effects
cytokines
leukocytes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01978/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01978/full

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