Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads

Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads

In female mammals, germ cells enter meiosis in the fetal ovaries, while in males, meiosis is prevented until postnatal development. Retinoic acid (RA) is considered the main inducer of meiotic entry, as it stimulates <i>Stra8</i> which is required for the mitotic/meiotic switch. In fetal...

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Bibliographic Details
Main Authors: Laura Bellutti, Emilie Abby, Sophie Tourpin, Sébastien Messiaen, Delphine Moison, Emilie Trautmann, Marie-Justine Guerquin, Virginie Rouiller-Fabre, René Habert, Gabriel Livera
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Biomolecules
Subjects:
meiotic entry
retinoic acid
cyp26-enzymes
fetal gonad
electroporation
Online Access:https://www.mdpi.com/2218-273X/9/10/536

Internet

https://www.mdpi.com/2218-273X/9/10/536

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