Focused Ultrasound Stimulates ER Localized Mechanosensitive PANNEXIN-1 to Mediate Intracellular Calcium Release in Invasive Cancer Cells

Focused Ultrasound Stimulates ER Localized Mechanosensitive PANNEXIN-1 to Mediate Intracellular Calcium Release in Invasive Cancer Cells

Focused ultrasound (FUS) is a rapidly developing stimulus technology with the potential to uncover novel mechanosensory dependent cellular processes. Since it is non-invasive, it holds great promise for future therapeutic applications in patients used either alone or as a complement to boost existin...

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Bibliographic Details
Main Authors: Nan Sook Lee, Chi Woo Yoon, Qing Wang, Sunho Moon, Kweon Mo Koo, Hayong Jung, Ruimin Chen, Laiming Jiang, Gengxi Lu, Antony Fernandez, Robert H. Chow, Andrew C. Weitz, Paul M. Salvaterra, Fabien Pinaud, K. Kirk Shung
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mechanotranduction
focused ultrasound (FUS)
calcium signaling
pannexin 1 (Panx1)
ATP
invasive cancer cells
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00504/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00504/full

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