Immunological Hallmarks of Inflammatory Status in Vaso-Occlusive Crisis of Sickle Cell Anemia Patients

Sickle Cell Anemia (SCA) is the most common genetic disorder around the world. The mutation in the β-globin gene is responsible for a higher hemolysis rate, with further involvement of immunological molecules, especially cytokines, chemokines, growth factors, and anaphylatoxins. These molecules are...

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Bibliographic Details
Main Authors: Alexander Leonardo Silva-Junior, Nadja Pinto Garcia, Evilázio Cunha Cardoso, Stephanny Dias, Andrea Monteiro Tarragô, Nelson Abrahim Fraiji, Matheus Souza Gomes, Laurence Rodrigues Amaral, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Erich Vinicius De Paula, Allyson Guimarães Costa, Adriana Malheiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.559925/full