Synthesis, Antitumor Evaluation, Molecular Modeling and Quantitative Structure–Activity Relationship (QSAR) of Novel 2-[(4-Amino-6-<i>N</i>-substituted-1,3,5-triazin-2-yl)methylthio]-4-chloro-5-methyl-<i>N</i>-(1<i>H</i>-benzo[<i>d</i>]imidazol-2(3<i>H</i>)-ylidene)Benzenesulfonamides

Synthesis, Antitumor Evaluation, Molecular Modeling and Quantitative Structure–Activity Relationship (QSAR) of Novel 2-[(4-Amino-6-<i>N</i>-substituted-1,3,5-triazin-2-yl)methylthio]-4-chloro-5-methyl-<i>N</i>-(1<i>H</i>-benzo[<i>d</i>]imidazol-2(3<i>H</i>)-ylidene)Benzenesulfonamides

A series of novel 2-[(4-amino-6-R<sup>2</sup>-1,3,5-triazin-2-yl)methylthio]-4-chloro-5-methyl-<i>N</i>-(5-R<sup>1</sup>-<i>1H</i>-benzo[<i>d</i>]imidazol-2(<i>3H</i>)-ylidene)benzenesulfonamides <b>6</b>–<b>49...

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Bibliographic Details
Main Authors: Łukasz Tomorowicz, Jarosław Sławiński, Beata Żołnowska, Krzysztof Szafrański, Anna Kawiak
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
benzenesulfonamide
synthesis
1,3,5-triazines
cytotoxicity
QSAR
molecular docking
Online Access:https://www.mdpi.com/1422-0067/21/8/2924

Internet

https://www.mdpi.com/1422-0067/21/8/2924

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