Identification of potential new protein vaccine candidates through pan-surfomic analysis of pneumococcal clinical isolates from adults.

Purified polysaccharide and conjugate vaccines are widely used for preventing infections in adults and in children against the Gram-positive bacterium Streptococcus pneumoniae, a pathogen responsible for high morbidity and mortality rates, especially in developing countries. However, these polysacch...

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Bibliographic Details
Main Authors: Alfonso Olaya-Abril, Irene Jiménez-Munguía, Lidia Gómez-Gascón, Ignacio Obando, Manuel J Rodríguez-Ortega
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720901?pdf=render