Hypopigmented burn hypertrophic scar contains melanocytes that can be signaled to re-pigment by synthetic alpha-melanocyte stimulating hormone in vitro.

There are limited treatments for dyschromia in burn hypertrophic scars (HTSs). Initial work in Duroc pig models showed that regions of scar that are light or dark have equal numbers of melanocytes. This study aims to confirm melanocyte presence in regions of hypo- and hyper-pigmentation in an animal...

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Bibliographic Details
Main Authors: Bonnie C Carney, Taryn E Travis, Lauren T Moffatt, Laura S Johnson, Melissa M McLawhorn, Cynthia M Simbulan-Rosenthal, Dean S Rosenthal, Jeffrey W Shupp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0248985