P2Y6 Receptor-Mediated Spinal Microglial Activation in Neuropathic Pain

Objective. To explore the role of purine family member P2Y6 receptors in regulating neuropathic pain (NP) via neuroinflammation in the spinal cord. Methods. Chronic constriction injury of the sciatic nerve (CCI) of NP was classic in setting up models on Sprague-Dawley (SD) rats. Experiments were per...

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Bibliographic Details
Main Authors: Jiang Bian, Ying Zhang, Yan Liu, Qun Li, Hai-bin Tang, Qing Liu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2019/2612534