Limitations of MTT and MTS-based assays for measurement of antiproliferative activity of green tea polyphenols.

The chemopreventive effect of green tea polyphenols, such as (-)-epigallocatechin-3-gallate (EGCG), has been well demonstrated in cell culture studies. However, a wide range of IC(50) concentrations has been observed in published studies of the anti-proliferative activity of EGCG from different labo...

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Bibliographic Details
Main Authors: Piwen Wang, Susanne M Henning, David Heber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2855713?pdf=render