CFTR regulates B cell activation and lymphoid follicle development

CFTR regulates B cell activation and lymphoid follicle development

Abstract Background Cystic fibrosis (CF) is an inherited disorder caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that promotes persistent lung infection and inflammation and progressive loss of lung function. Patients with CF have increased lung lymphoid follicles (LFs...

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Bibliographic Details
Main Authors: Francesca Polverino, Bao Lu, Joselyn Rojas Quintero, Sara O. Vargas, Avignat S. Patel, Caroline A. Owen, Norma P. Gerard, Craig Gerard, Manuela Cernadas
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Respiratory Research
Subjects:
Cystic fibrosis
B lymphocyte
Lymphoid follicles
BAFF
Online Access:http://link.springer.com/article/10.1186/s12931-019-1103-1

Internet

http://link.springer.com/article/10.1186/s12931-019-1103-1

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