Chemotherapy-induced cognitive impairment is associated with decreases in cell proliferation and histone modifications

<p>Abstract</p> <p>Background</p> <p>In this study, we examined the effects of cyclophosphamide, methothrexate, and 5-Fluorouracil (CMF) drug combination on various aspects of learning and memory. We also examined the effects of CMF on cell proliferation and chromatin r...

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Bibliographic Details
Main Authors: Briones Teresita L, Woods Julie
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/124