The Sulfilimine Analogue of Allicin, <i>S</i>-Allyl-<i>S</i>-(<i>S</i>-allyl)-<i>N</i>-Cyanosulfilimine, Is Antimicrobial and Reacts with Glutathione

When cells of garlic (<i>Allium sativum</i>) are disrupted by wounding, they produce the defense substance allicin (diallylthiosulfinate). Allicin is an efficient thiol trap and readily passes through cell membranes into the cytosol, where it behaves as a redox toxin by oxidizing the cel...

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Bibliographic Details
Main Authors: Tobias Horn, Wolfgang Bettray, Ulrike Noll, Felix Krauskopf, Meng-Ruo Huang, Carsten Bolm, Alan J. Slusarenko, Martin C. H. Gruhlke
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/11/1086