Identification and validation of the miRNA–mRNA regulatory network in fetoplacental arterial endothelial cells of gestational diabetes mellitus

Identification and validation of the miRNA–mRNA regulatory network in fetoplacental arterial endothelial cells of gestational diabetes mellitus

Gestational diabetes mellitus (GDM) increases the risk of fetal heart malformations, though little is known about the mechanism of hyperglycemia-induced heart malformations. Thus, we aimed to reveal the global landscape of miRNAs and mRNAs in GDM-exposed fetoplacental arterial endothelial cells (dAE...

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Bibliographic Details
Main Authors: Longkai He, Xiaotong Wang, Ya Jin, Weipeng Xu, Yi Guan, Jingchao Wu, Shasha Han, Guosheng Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
mirna-mrna network
fetoplacental endothelial cells
gestational diabetes mellitus
heart development
cardiac hypertrophy
bioinformatics analysis
Online Access:http://dx.doi.org/10.1080/21655979.2021.1950279

Internet

http://dx.doi.org/10.1080/21655979.2021.1950279

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