Glycogen Synthase Kinase-3 Beta Expression Correlates With Worse Overall Survival in Non-Small Cell Lung Cancer—A Clinicopathological Series

Glycogen Synthase Kinase-3 Beta Expression Correlates With Worse Overall Survival in Non-Small Cell Lung Cancer—A Clinicopathological Series

BackgroundGlycogen Synthase Kinase-3 beta (GSK-3β) regulates diverse cell functions including metabolic activity, signaling and structural proteins. GSK-3β phosphorylates target pro-oncogenes and regulates programmed cell death-ligand 1 (PD-L1). This study investigated the correlation between GSK-3β...

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Bibliographic Details
Main Authors: Marclesson Alves, Daniela de Paula Borges, Aline Kimberly, Francisco Martins Neto, Ana Claudia Oliveira, Juliana Cordeiro de Sousa, Cleto D. Nogueira, Benedito A. Carneiro, Fabio Tavora
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
glycogen synthase kinase-3 beta (GSK-3 beta)
lung cancer
non-small cell carcinoma
immunotherapy
programmed death-ligand 1 (PD-L1)
phosphatase and tensin homolog deleted on chromosome 10 (PTEN)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.621050/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.621050/full

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