The role of activated NLRP3 inflammatory body in acute kidney injury in rats caused by sepsis and NLRP3-TXNIP signaling pathway

Objective: The model of acute renal injury (AKI) induced by sepsis in rats was established by abdominal resection through surgical suture. The activation mechanism of nod-like receptor with pyrin domain containing 3 (NLRP3) inflammatory corpuscle in AKI induced by sepsis was analyzed. Methods: Here,...

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Bibliographic Details
Main Authors: Huanghao Deng, Fangzhi Chen, Yinhuai Wang, Hongyi Jiang, Zhitao Dong, Biao Yuan, Xiaokun Zhao
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Saudi Journal of Biological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X20300942