Predictive long-range allele-specific mapping of regulatory variants and target transcripts.

Genome-wide association studies (GWASs) have identified a large number of noncoding associations, calling for systematic mapping to causal regulatory variants and their distal target genes. A widely used method, quantitative trait loci (QTL) mapping for chromatin or expression traits, suffers from s...

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Bibliographic Details
Main Authors: Kibaick Lee, Seulkee Lee, Hyoeun Bang, Jung Kyoon Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5391085?pdf=render