Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival

Myelin, made by oligodendrocytes, is essential for rapid information transfer in the central nervous system. Oligodendrocyte precursors (OPs) receive glutamatergic synaptic input from axons but how this affects their development is unclear. Murine OPs in white matter express AMPA receptor (AMPAR) su...

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Bibliographic Details
Main Authors: Eleni Kougioumtzidou, Takahiro Shimizu, Nicola B Hamilton, Koujiro Tohyama, Rolf Sprengel, Hannah Monyer, David Attwell, William D Richardson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
oligodendrocyte
survival
glutamate
AMPA receptor
conditional knockout
internode length
Online Access:https://elifesciences.org/articles/28080

Internet

https://elifesciences.org/articles/28080

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