T Cell Receptor Genotype and <i>Ubash3a</i> Determine Susceptibility to Rat Autoimmune Diabetes
Genetic analyses of human type 1 diabetes (T1D) have yet to reveal a complete pathophysiologic mechanism. Inbred rats with a high-risk class II major histocompatibility complex (MHC) haplotype (RT1B/D<sup>u</sup>) can illuminate such mechanisms. Using T1D-susceptible LEW.1WR1 rats that e...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-06-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/12/6/852 |