Synthesis and Activity of a New Series of(Z)-3-Phenyl-2-benzoylpropenoic Acid Derivatives as Aldose Reductase Inhibitors

During the course of studies directed towards the discovery of novel aldose reductase inhibitors for the treatment of diabetic complications, we synthesized a series of new (Z)-3-phenyl-2-benzoylpropenoic acid derivatives and tested their in vitro inhibitory activities on rat lens aldose reductase....

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Bibliographic Details
Main Authors: Shao-Jie Wang, Ju-Fang Yan, Dong Hao, Xin-Wen Niu, Mao-Sheng Cheng
Format: Article
Language:English
Published: MDPI AG 2007-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/12/4/885/