A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus.

Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a β-Herpesvirus that infects the majority of the world's population and causes disease in neonates and immunocompromised adults. CD8(+) T cells are a major part of the immune response to MCMV and HCMV. P...

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Bibliographic Details
Main Authors: Sarah Hutchinson, Stuart Sims, Geraldine O'Hara, Jon Silk, Uzi Gileadi, Vincenzo Cerundolo, Paul Klenerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3033404?pdf=render