RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies.

The chemokine RANTES (regulated on activation, normal T-cell expressed and secreted)/CCL5 is involved in the pathogenesis of cardiovascular disease in mice, whereas less is known in humans. We hypothesised that its relevance for atherosclerosis should be reflected by associations between CCL5 gene v...

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Main Authors: Christian Herder, Wouter Peeters, Thomas Illig, Jens Baumert, Dominique P V de Kleijn, Frans L Moll, Ulrike Poschen, Norman Klopp, Martina Müller-Nurasyid, Michael Roden, Michael Preuss, CARDIoGRAM Consortium, Mahir Karakas, Christa Meisinger, Barbara Thorand, Gerard Pasterkamp, Wolfgang Koenig, Themistocles L Assimes, Panos Deloukas, Jeanette Erdmann, Hilma Holm, Sekar Kathiresan, Inke R König, Ruth McPherson, Muredach P Reilly, Robert Roberts, Nilesh J Samani, Heribert Schunkert, Alexandre F R Stewart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3232218?pdf=render