Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep.

Long-term changes in dopaminergic signaling are thought to underlie the pathophysiology of a number of psychiatric disorders. Several conditions are associated with cognitive deficits such as disturbances in attention processes and learning and memory, suggesting that persistent changes in dopaminer...

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Bibliographic Details
Main Authors: Kafui Dzirasa, Lucas M Santos, Sidarta Ribeiro, Jennifer Stapleton, Raul R Gainetdinov, Marc G Caron, Miguel A L Nicolelis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2668764?pdf=render