Transcriptome analysis of skeletal muscles revealed the effect of exercise on the molecular mechanisms regulating muscle growth and metabolism in patients with heart failure

Transcriptome analysis of skeletal muscles revealed the effect of exercise on the molecular mechanisms regulating muscle growth and metabolism in patients with heart failure

Aim. Heart failure (HF) is accompanied by skeletal muscle atrophy and exercise intolerance. The aim was to study the molecular mechanisms underlying the therapeutic effect of personalized exercise in patients with HF.Material and methods. RNA sequencing obtained from skeletal muscle biopsies before...

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Bibliographic Details
Main Authors: O. A. Ivanova, E. V. Ignatieva, T. A. Lelyavina, V. L. Galenko, M. Yu. Komarova, M. A. Bortsova, M. Yu. Sitnikova, A. A. Kostareva, A. A. Sergushichev, R. I. Dmitrieva
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC  2020-11-01
Series:Российский кардиологический журнал
Subjects:
heart failure
exercise
skeletal muscle atrophy
rna sequencing
signaling pathways
gene expression
Online Access:https://russjcardiol.elpub.ru/jour/article/view/4132

Internet

https://russjcardiol.elpub.ru/jour/article/view/4132

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