CReVIS-Seq: A highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites

Lentiviruses have been widely used as a means of transferring exogenous DNAs into human cells to treat various genetic diseases. Lentiviral vectors are fundamentally integrated into the host genome, but their integration sites are generally unpredictable, which may increase the uncertainty for their...

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Bibliographic Details
Main Authors: Heon Seok Kim, Gue-Ho Hwang, Hyomin K. Lee, Taegeun Bae, Seong-Ho Park, Yong Jun Kim, Sun Lee, Jae-Hoon Park, Sangsu Bae, Junho K. Hur
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120302163