DeepShape: estimating isoform-level ribosome abundance and distribution with Ribo-seq data

DeepShape: estimating isoform-level ribosome abundance and distribution with Ribo-seq data

Abstract Background Ribosome profiling brings insight to the process of translation. A basic step in profile construction at transcript level is to map Ribo-seq data to transcripts, and then assign a huge number of multiple-mapped reads to similar isoforms. Existing methods either discard the multip...

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Bibliographic Details
Main Authors: Hongfei Cui, Hailin Hu, Jianyang Zeng, Ting Chen
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Ribo-seq
Translation
Transcript-level
Multiple alignment
Online Access:https://doi.org/10.1186/s12859-019-3244-0

Internet

https://doi.org/10.1186/s12859-019-3244-0

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