Bacterial RecA Protein Promotes Adenoviral Recombination during In Vitro Infection

Adenoviruses are common human mucosal pathogens of the gastrointestinal, respiratory, and genitourinary tracts and ocular surface. Here, we report finding Chi-like sequences in adenovirus recombination hot spots. Adenovirus coinfection in the presence of bacterial RecA protein facilitated homologous...

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Bibliographic Details
Main Authors: Jeong Yoon Lee, Ji Sun Lee, Emma C. Materne, Rahul Rajala, Ashrafali M. Ismail, Donald Seto, David W. Dyer, Jaya Rajaiya, James Chodosh
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00105-18