Functional over-load saves motor units in the SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis
The fastest, most forceful motor units are lost progressively during asymptomatic disease in the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis. As the disease progresses the surviving motor units must increase their levels of activity to sustain posture and movement. If activity-d...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2010-02-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996109003076 |