Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes

Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes

Heat shock proteins (HSP) are a highly abundant class of molecular chaperones that can be released into the extracellular milieu and influence the immune response. HSP release can occur when cells undergo necrosis and exude their contents. However, HSPs are also secreted from intact cells, either in...

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Bibliographic Details
Main Authors: Ayesha Murshid, Thiago J. Borges, Cristina Bonorino, Benjamin J. Lang, Stuart K. Calderwood
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
heat shock proteins
scavenger receptor
immunity
macrophage
dendritic
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03035/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03035/full

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