NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?

The chemopreventive NO-donating NSAIDs (NO-NSAIDs; NSAIDs with an NO-releasing moiety) modulate PPARδ and offer the opportunity to revisit the controversial role of PPARδ in carcinogenesis (several papers report that PPARδ either promotes or inhibits cancer). This review summarizes the pharmacology...

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Bibliographic Details
Main Authors: Gerardo G. Mackenzie, Shaheen Rasheed, William Wertheim, Basil Rigas
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2008/919572