Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels
<p>Abstract</p> <p>Background</p> <p>AhR activates the transcription of several target genes including CYP1B1. Recently, we showed <it>CYP1B1 </it>as the major cytochrome P450 (CYP) enzyme expressed in human brain microvessels. Here, we studied the effect of...
Main Authors: | Jacob Aude, Hartz Anika MS, Potin Sophie, Coumoul Xavier, Yousif Salah, Scherrmann Jean-Michel, Bauer Björn, Declèves Xavier |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-08-01
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Series: | Fluids and Barriers of the CNS |
Subjects: | |
Online Access: | http://www.fluidsbarrierscns.com/content/8/1/23 |
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