Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels

Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels

<p>Abstract</p> <p>Background</p> <p>AhR activates the transcription of several target genes including CYP1B1. Recently, we showed <it>CYP1B1 </it>as the major cytochrome P450 (CYP) enzyme expressed in human brain microvessels. Here, we studied the effect of...

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Bibliographic Details
Main Authors: Jacob Aude, Hartz Anika MS, Potin Sophie, Coumoul Xavier, Yousif Salah, Scherrmann Jean-Michel, Bauer Björn, Declèves Xavier
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Fluids and Barriers of the CNS
Subjects:
Aryl hydrocarbon Receptor
Cyp1b1
TCDD
diesel exhaust particles
brain microvessels
Online Access:http://www.fluidsbarrierscns.com/content/8/1/23

Internet

http://www.fluidsbarrierscns.com/content/8/1/23

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